Kenneth Marek, MD
President and Senior Scientist

John Seibyl, MD
Executive Director and Senior Scientist
Danna Jennings, MD
Clinical Research Director
Gilles Tamagnan, PhD
Director of Laboratory Research and Development

Our physicians,radiochemists, research coordinators and research technologists have been recognized internationally for their special research expertise and have immense experience in the management of movement disorders and other neurodegenerative conditions. IND physicians, research technologists and scientists are focused on improving treatment for neurologic disorders. Our physicians and coordinators are actively involved and play leadership roles in the Parkinson's Study Group (PSG), Huntington Study Group (HSG) and the Dystonia Study Group (DSG). These groups are national consortiums aimed at advancing knowledge about the causes and developing more effective treatments for these conditions.

 

Kenneth Marek, MD is President and Senior Scientist at the Institute for Neurodegenerative Disorders. He graduated from Princeton University (AB, biochemistry) and received his medical degree from Yale University. Dr. Marek was trained in internal medicine and neurology at the Johns Hopkins School of Medicine and is board certified in both of these specialties. He received further training as a post-doctoral fellow in neurochemistry at the Institute of Neurology, Queens Square, London. He has been a faculty member in the departments of neurology at Johns Hopkins University and Yale University.

Dr. Marek has been the recipient of numerous grants and awards including those from the National Institute of Health, Department of Defense, American Heart Association, Parkinson's Disease Foundation, and National Parkinson's Foundation and has been a recipient of the National Parkinson's Foundation Richard E. Heikkala Research Scholar Award. He has served on the executive committee of the Parkinson Study Group and in leadership roles in the Huntington Study Group. He serves on the research advisory committee of the Huntington Disease Society of America and the scientific advisory board of the Michael J Fox Foundation. He also was a co-founder of Molecular NeuroImaging, LLC, (MNI) a company providing clinical neuroimaging research services.

Dr. Marek's major research interests include identification of biomarkers for early detection, assessment of disease progression and development of new treatments for Parkinson disease and related neurodegenerative disorders. His specific interest has been in vivo neuroreceptor imaging in Parkinson disease and related disorders. He has authored numerous neurology and neuroscience publications on these topics. Dr. Marek is the principal investigator of several multi-center international studies investigating the use of imaging to assess the onset, progression, and effect of treatment in Parkinson disease.

 

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John Seibyl, MD is Executive Director and Senior Scientist at the Institute for Neurodegenerative Disorders and President of Molecular NeuroImaging, LLC, (MNI) a company providing clinical neuroimaging research services. He was previously Chief of the Section of Nuclear Medicine and Associate Professor of Diagnostic Radiology and Psychiatry, Yale University School of Medicine until July 2001. He is board-certified in both Psychiatry and Nuclear Medicine. He received his undergraduate degree at Yale University and completed his medical degree at Case Western Reserve University in Cleveland, Ohio.

Dr. Seibyl trained as a post-doctoral fellow in the Department of Psychiatry at Yale University where he won the Seymour Lustman Research Prize in the Department of Psychiatry two consecutive years. He joined the faculty upon completion of this training. While on the Psychiatry faculty, Dr. Seibyl's interest in brain imaging led to his returning for a training Fellowship in Nuclear Medicine at Yale under Dr. Paul Hoffer. He was recruited to the Diagnostic Radiology faculty and appointed Director of the NeuroSPECT Center, a clinical brain imaging research lab in the Section of Nuclear Medicine. Dr. Seibyl subsequently became Chief of the Section of Nuclear Medicine and Director of the Yale-VA PET Center.

Dr. Seibyl has won numerous grants and contracts in the context of his work in brain imaging. He serves on the editorial board of the European Journal of Nuclear Medicine and is a frequent reviewer for top-tier nuclear imaging journals. He serves on international panels for his work in neurodegenerative disease research and, working with Dr. Marek, established the former NeuroSPECT Center at Yale University as the premier Parkinson brain imaging research center. Recent projects include the development of a web-based normal brain image database and on-going work applying brain imaging techniques to improve the diagnosis and assessment of disease status in patients with neurodegenerative diseases.

 

 

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Danna Jennings, MD is Clinical Research Director at the Institute for Neurodegenerative Disorders. She received her medical degree from Oregon Health & Science University. Dr. Jennings received her training in Neurology from Boston University and completed a movement disorders fellowship at Columbia Presbyterian Medical Center in New York. She was a teaching faculty member in the department of neurology at Yale University prior to her position at the Institute for Neurodegenerative Disorders.  

 

Dr. Jennings has been an active member of the Parkinson's Study Group, the Huntington Study Group and the Dystonia Study Group. She has served as investigator on over 15 clinical trials aimed at the development of improvements in the diagnosis and treatment of neurodegenerative conditions. Dr. Jennings' specific research interests include the development of accurate diagnostic tests to detect changes in the brain that may occur even prior to symptoms in neurodegenerative conditions. She is currently involved in several studies aimed at the development of medications that may modify the rate of progression of Parkinson's disease In addition, she has designed studies that focus on developing a better understanding of risk factors that may play a role in the rate of progression of Parkinson disease.

 

Gilles Tamagnan, PhD is Laboratory Research and Development Director. Dr. Tamagnan received his PhD in Medicinal Chemistry at the University Joseph Fourier in Grenoble, France in 1993. After a post-doctoral fellowship spent on the crystallization of protein, Dr. Tamagnan completed a second postdoctoral fellowship at RBI in Boston, Massachusetts. His research subject was to develop new ligands for the diagnosis of Parkinson disease using compounds labeled with radioactive atoms. He joined the NeuroImaging program at Yale University in June 1997 to work on the development of new radioligands to study neurodegenerative diseases and came to IND in 2003. Dr. Tamagnan has been the recipient of numerous grants and is the co-inventor of ligands used for the diagnosis of Parkinson disease. He joined IND as Laboratory Research and Development Director in 2003.