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Kenneth Marek, M.D. - President and Senior
Scientist
John Seibyl, M.D. - Executive Director
Danna Jennings, M.D .- Clinical Research
Director
David S. Russell, M.D. - Ph.D. Associate
Clinical Research Director
Gilles Tamagnan, Ph.D. - Director of
Laboratory Research and Development
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Our physicians,radiochemists,
research coordinators and research technologists have been recognized
internationally for their special research expertise and have immense
experience in the management of movement disorders and other neurodegenerative
conditions. IND physicians, research technologists and scientists
are focused on improving treatment for neurologic disorders. Our
physicians and coordinators are actively involved and play leadership
roles in the Parkinson's Study Group (PSG), Huntington Study Group
(HSG) and the Dystonia Study Group (DSG). These groups are national
consortiums aimed at advancing knowledge about the causes and developing
more effective treatments for these conditions.
| Kenneth Marek, MD is
President and Senior Scientist at the Institute for Neurodegenerative
Disorders. He graduated from Princeton University (AB, biochemistry)
and received his medical degree from Yale University. Dr. Marek
was trained in internal medicine and neurology at the Johns
Hopkins School of Medicine and is board certified in both of
these specialties. He received further training as a post-doctoral
fellow in neurochemistry at the Institute of Neurology, Queens
Square, London. He has been a faculty member in the departments
of neurology at Johns Hopkins University and Yale University. |
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Dr. Marek has been the recipient of numerous grants and awards
including those from the National Institute of Health, Department
of Defense, American Heart Association, Parkinson's Disease Foundation,
and National Parkinson's Foundation and has been a recipient of
the National Parkinson's Foundation Richard E. Heikkala Research
Scholar Award. He has served on the executive committee of the Parkinson
Study Group and in leadership roles in the Huntington Study Group.
He serves on the research advisory committee of the Huntington Disease
Society of America and the scientific advisory board of the Michael
J Fox Foundation. He also was a co-founder of Molecular NeuroImaging,
LLC, (MNI) a company providing clinical neuroimaging research services.
Dr. Marek's major research interests include identification of biomarkers
for early detection, assessment of disease progression and development
of new treatments for Parkinson disease and related neurodegenerative
disorders. His specific interest has been in vivo neuroreceptor
imaging in Parkinson disease and related disorders. He has authored
numerous neurology and neuroscience publications on these topics.
Dr. Marek is the principal investigator of several multi-center
international studies investigating the use of imaging to assess
the onset, progression, and effect of treatment in Parkinson disease.
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John Seibyl, MD is Executive
Director and Senior Scientist at the Institute for Neurodegenerative
Disorders and President of Molecular NeuroImaging, LLC, (MNI)
a company providing clinical neuroimaging research services.
He was previously Chief of the Section of Nuclear Medicine and
Associate Professor of Diagnostic Radiology and Psychiatry,
Yale University School of Medicine until July 2001. He is board-certified
in both Psychiatry and Nuclear Medicine. He received his undergraduate
degree at Yale University and completed his medical degree at
Case Western Reserve University in Cleveland, Ohio. |
Dr. Seibyl trained as a post-doctoral fellow in the Department
of Psychiatry at Yale University where he won the Seymour Lustman
Research Prize in the Department of Psychiatry two consecutive years.
He joined the faculty upon completion of this training. While on
the Psychiatry faculty, Dr. Seibyl's interest in brain imaging led
to his returning for a training Fellowship in Nuclear Medicine at
Yale under Dr. Paul Hoffer. He was recruited to the Diagnostic Radiology
faculty and appointed Director of the NeuroSPECT Center, a clinical
brain imaging research lab in the Section of Nuclear Medicine. Dr.
Seibyl subsequently became Chief of the Section of Nuclear Medicine
and Director of the Yale-VA PET Center.
Dr. Seibyl has won numerous grants and contracts in the context
of his work in brain imaging. He serves on the editorial board of
the European Journal of Nuclear Medicine and is a frequent reviewer
for top-tier nuclear imaging journals. He serves on international
panels for his work in neurodegenerative disease research and, working
with Dr. Marek, established the former NeuroSPECT Center at Yale
University as the premier Parkinson brain imaging research center.
Recent projects include the development of a web-based normal brain
image database and on-going work applying brain imaging techniques
to improve the diagnosis and assessment of disease status in patients
with neurodegenerative diseases.
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Danna
Jennings, MD is Clinical Research Director at the Institute for
Neurodegenerative Disorders.
She received her medical degree from
Oregon Health & Science University. Dr. Jennings received her
training in Neurology from Boston University and completed a movement
disorders fellowship at Columbia Presbyterian Medical Center in New
York. She was a teaching faculty member in the department of neurology
at Yale University prior to her position at the Institute for Neurodegenerative
Disorders. |
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Dr. Jennings has been an active member of the
Parkinson's Study Group, the Huntington Study Group and the Dystonia
Study Group. She has served as investigator on over 15 clinical
trials aimed at the development of improvements in the diagnosis
and treatment of neurodegenerative conditions. Dr. Jennings' specific
research interests include the development of accurate diagnostic
tests to detect changes in the brain that may occur even prior to
symptoms in neurodegenerative conditions. She is currently involved
in several studies aimed at the development of medications that
may modify the rate of progression of Parkinson's disease In addition,
she has designed studies that focus on developing a better understanding
of risk factors that may play a role in the rate of progression
of Parkinson disease.
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David S. Russell, M.D., Ph.D.
Associate Clinical Research Director
Dr. Russell is an Associate Clinical Research Director at IND.
Prior to coming to IND, he was a member of the Yale Movement
Disorders Clinics, since 1995 and is an Assistant Clinical Professor
at the Yale University School of Medicine. He has directed a number
of basic scientific studies related to dopaminergic brain function
for over a decade. Additionally, he has been an active participant
in the Parkinson Study Group and served as an investigator in
multi-site clinical trials of Parkinson disease. In 2007, he
expanded his role in clinical trials of neurodegenerative disorders
by joining the MNI. He received his undergraduate training in
Biology at Oberlin College and completed a Medical Scientist
Training Program (M.D., Ph.D.) at Cornell University Medical College
and the Sloan-Kettering Institute in New York. His internship in
Internal Medicine and residency in Neurology were performed at
Yale-New Haven Hospital and he was selected as Chief Resident in
Neurology for 1994-1995. Dr. Russell’s research and clinical
interested include investigations of the mechanisms and potential
prevention of neuronal dysfunction, as well as development of early
molecular and biomarker indicators of loss or alteration of function
of specific brain systems. He has published widely in important
neuroscience journals and spoken at numerous national and
international meetings.
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Gilles Tamagnan, PhD
is Laboratory Research and Development Director. Dr. Tamagnan received
his PhD in Medicinal Chemistry at the University Joseph Fourier
in Grenoble, France in 1993. After a post-doctoral fellowship spent
on the crystallization of protein, Dr. Tamagnan completed a second
postdoctoral fellowship at RBI in Boston, Massachusetts. His research
subject was to develop new ligands for the diagnosis of Parkinson
disease using compounds labeled with radioactive atoms. He joined
the NeuroImaging program at Yale University in June 1997 to work
on the development of new radioligands to study neurodegenerative
diseases and came to IND in 2003. Dr. Tamagnan has been the recipient
of numerous grants and is the co-inventor of ligands used for the
diagnosis of Parkinson disease. He joined IND as Laboratory Research
and Development Director in 2003.
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